Now available at Go Leaner

Wegovy 7.2 mg

The highest semaglutide dose, approved in the EU in 2026. An average 20.7% weight loss in the STEP UP trial. Available now at Go Leaner, under medical supervision.

EU-approved 2026
Once weekly
Care plan €199/month

What is Wegovy 7.2 mg?

Wegovy 7.2 mg is a new, higher maintenance dose of semaglutide for adults with obesity for whom 2.4 mg per week gives insufficient results or whose weight loss has plateaued. It is the same active substance as the existing Wegovy pen, at three times the dose.

The European Commission approved Wegovy 7.2 mg in 2026 on the basis of the STEP UP programme. Novo Nordisk launched the dose in Europe in the third quarter of 2026, in a single-use pen.

Want the basics first? See our page on Wegovy (2.4 mg), the standard titration schedule and the STEP-1 results.

STEP UP: the evidence for 7.2 mg

STEP UP was a randomised, double-blind, 72-week trial in 1,407 adults with obesity without diabetes. Participants received 7.2 mg, 2.4 mg or placebo, all alongside lifestyle support.

Treatment group	Average weight loss	≥20%	≥25%
Semaglutide 7.2 mg	-20.7%	approx. 50%	approx. 33%
Semaglutide 2.4 mg	-17.5%	approx. 36%	approx. 17%
Placebo + lifestyle	-2.4%	approx. 2%	approx. 1%

STEP UP; results presented at EASD 2025 and the European Congress on Obesity 2026, Novo Nordisk.

Results vary per person and depend on lifestyle, starting weight and tolerability. The ≥20% and ≥25% figures are rounded.

A further analysis showed that early responders on 7.2 mg lost up to almost 28% of their body weight on average. In people with obesity and type 2 diabetes (STEP UP T2D), average weight loss was 14.1%.

Dose and titration

Wegovy 7.2 mg is not a starting dose. You first titrate up on the standard Wegovy schedule to 2.4 mg. Only then does the doctor assess whether a further increase makes sense.

Period	Dose	Note
Weeks 1 to 16	0.25 → 1.7 mg	Standard titration, as with Wegovy 2.4 mg
Week 17+	2.4 mg/week	First maintenance dose; enough for many people
After ≥ 4 weeks on 2.4 mg	4.8 mg/week	Intermediate step, only if well tolerated
After ≥ 4 weeks on 4.8 mg	7.2 mg/week	Highest maintenance dose

Each step lasts at least four weeks. If you have side effects you stay longer on a step or go back one. The doctor sets the pace based on your tolerability and results, never on a fixed calendar.

Who is 7.2 mg for?

You have been on Wegovy 2.4 mg for at least four weeks and tolerate it well
Your weight loss has plateaued before you reached your goal
You have a higher starting weight or a BMI above 35, where more weight loss is medically desirable
Your doctor sees no reason to switch to tirzepatide (Mounjaro)

Not suitable if

You are not yet on 2.4 mg, or do not tolerate that dose well
You are pregnant, planning a pregnancy or breastfeeding
You have a personal or family history of medullary thyroid carcinoma or MEN2

Side effects at 7.2 mg

The side effects are the same as at lower semaglutide doses, mainly gastrointestinal. In STEP UP they were slightly more frequent at 7.2 mg than at 2.4 mg, mostly mild to moderate and mainly during titration. Discontinuation due to side effects was low and similar between the two doses.

Common

Nausea
Diarrhoea or constipation
Vomiting (mainly in the first weeks on a new step)
Reduced appetite, feeling full
Fatigue, headache

Rare, contact us immediately

Severe, persistent abdominal pain (pancreatitis)
Gallstone symptoms
Severe dehydration from persistent vomiting
Allergic reaction

At Go Leaner your doctor supervises every dose step. Between steps you complete check-ins in the app, so we see side effects before they become a problem.

What does Wegovy 7.2 mg cost at Go Leaner?

At Go Leaner you pay a fixed Basic Plan of €199 per month, whatever your dose. That covers the intake, blood tests, the doctor, coaching and the app. The medication itself is paid separately at pharmacy price; that rises with the dose, so 7.2 mg costs more than 2.4 mg. We add no mark-up. With many online providers the medication is bundled into a monthly fee that rises with every dose step, and 7.2 mg is often not even available yet.

Medical intake in person in Amstelveen or Aalsmeer, including blood tests
Monthly doctor review, tapering support and the prescription
Lifestyle coaching and the Go Leaner app
No mark-up on the medication price, including 7.2 mg

See prices →

Wegovy 7.2 mg or Mounjaro?

Wegovy 7.2 mg (20.7% in STEP UP, 72 weeks) comes close to tirzepatide (Mounjaro, 20.9% at 15 mg in SURMOUNT-1, 72 weeks). The difference is the mechanism: semaglutide acts on one hormone receptor (GLP-1), tirzepatide on two (GLP-1 and GIP). Which suits you better depends on tolerability, history and how you have responded to semaglutide. If you respond well to Wegovy, you do not need to switch medicines to go further.

Compare with Mounjaro →

Frequently asked questions

Is Wegovy 7.2 mg available in the Netherlands yet?

Yes. Wegovy 7.2 mg was approved in the EU in 2026 and launched in the third quarter of 2026. At Go Leaner the dose is available now for patients on 2.4 mg for whom the doctor considers an increase appropriate.

Can I start on 7.2 mg straight away?

No. You always titrate up first via the standard schedule to 2.4 mg. Only after at least four weeks on 2.4 mg, and if well tolerated, can the doctor increase via 4.8 mg to 7.2 mg.

How much extra weight loss does 7.2 mg give compared with 2.4 mg?

In STEP UP, just over 3 percentage points more on average: 20.7% versus 17.5% after 72 weeks. The share of people losing 25% or more roughly doubled.

Is Wegovy 7.2 mg reimbursed?

No. Like Wegovy 2.4 mg, it is not reimbursed from basic health insurance in the Netherlands for weight loss. At Go Leaner you pay for the medication separately at pharmacy price, with no mark-up; the Basic Plan stays €199 per month.

Are the side effects worse at 7.2 mg?

Slightly more frequent, not more severe. Mainly nausea and gastrointestinal complaints during titration. That is why the increase is made in steps of at least four weeks, under medical supervision.

What if I already use Wegovy with another provider?

You can switch. Bring your latest prescription or packaging to the intake. After blood tests and assessment by our doctor we continue your treatment at your current dose and decide together whether 7.2 mg makes sense.

Wegovy 7.2 mg is a prescription medicine. Use only under medical supervision. This information is for information only and does not replace medical advice.